Identification of post-cardiac arrest blood pressure thresholds associated with outcomes in children: an ICU-Resuscitation study

Table 4 Intra-arrest hemodynamics and chest compression mechanics by systolic and diastolic blood pressure thresholds 0–6 h post

	Post-arrest systolic BP (0–6 h)^a		P value	Post-arrest diastolic BP (0–6 h)^a		P value
	> 10th percentile (N = 100)	< 10th percentile (N = 127)	P value	> 50th percentile (N = 121)	< 50th percentile (N = 106)	P value
Intra-arrest event characteristics
Average systolic blood pressure (mmHg)
Age ≤ 1 year	82.0 [68.9, 103.3]	72.2 [58.4, 87.9]	0.006^c	81.7 [64.8, 94.8]	67.2 [54.6, 82.3]	0.004^c
Age > 1 year	101.6 [85.1, 124.6]	90.3 [69.3, 116.2]	0.205^c	104.5 [95.1, 127.1]	90.3 [72.6, 115.4]	0.070^c
Average systolic blood pressure ≥ 60 mmHg for age < 1 year or ≥ 80 mmHg for age ≥ 1 year	78 (78.0%)	87 (68.5%)	0.283^b	96 (79.3%)	69 (65.1%)	0.009^b
Average diastolic blood pressure (mmHg)
Age ≤ 1 year	41.1 [32.3, 48.6]	36.3 [30.1, 47.0]	0.176^c	41.5 [32.0, 49.9]	34.6 [29.5, 46.0]	0.026^c
Age > 1 year	43.4 [37.5, 60.6]	44.5 [34.5, 54.7]	0.628^c	53.8 [40.4, 63.7]	42.9 [34.5, 53.4]	0.052^c
Average diastolic blood pressure ≥ 25 mmHg for age < 1 year or ≥ 30 mmHg for age ≥ 1 year	92 (92.0%)	114 (89.8%)	0.648^b	112 (92.6%)	94 (88.7%)	0.363^b
Average chest compression rate over the first 10 min	121.6 [112.7, 132.7]	124.6 [113.4, 132.8]	0.719^c	121.97 [112.14, 132.00]	124.74 [116.30, 133.01]	0.256^c
Average chest compression fraction ≥ 0.80	96 (96.0%)	117 (92.1%)	0.276^b	116 (95.9%)	97 (91.5%)	0.268^b
Average chest compression fraction over the first 10 min	1.0 [0.9, 1.0]	1.0 [0.9, 1.0]	0.078^c	0.98 [0.95, 1.00]	0.98 [0.92, 1.00]	0.336^c

^aPost-arrest systolic or diastolic blood pressure thresholds defined as the minimum recorded systolic or diastolic blood pressure in the time period ≤ the 10th or 50th percentile for age, sex, and height, respectively
^bFishers Exact test
^cWilcoxon rank-sum test

ISSN: 1364-8535