Table 3 Effects of volume expansion on hemodynamic variables in fluid responders (upper panel) and non-responders (lower panel)
Before VE | After VE | p-value | |
|---|---|---|---|
Fluid responders n = 17 | |||
MAP–mmHg | 68 [61–77] | 83 [78–104] | < 0.0001 |
DAP–mmHg | 53 [47–58] | 64 [56–70] | 0.0002 |
CVP–mmHg | 6 [4–9] | 9 [5–12] | 0.002 |
CI–L/min/m2 | 2.34 [1.69–3.06] | 3.17 [2.28–4.03] | < 0.0001 |
HR–beats/min | 112 [72–116] | 107 [76–116] | 0.40 |
Blood temperature–°C | 37.0 [36.0–37.7] | 36.8 [35.7–37.4] | < 0.0001 |
Arterial lactate–mmol/L | 2.8 [2.0–4.6] | – | – |
Norepinephrine | |||
Rate—µg/kg/min | 0.56 [0.28–1.42] | 0.56 [0.28–1.42] | – |
Delay between initiation and CRT—hour | 18 [4–25] | – | |
CRT–s | 5.49 [3.02–7.57] | 3.41 [2.35–4.78] | < 0.0001 |
Fluid non-responders n = 16 | |||
MAP–mmHg | 72 [62–72] | 80 [70–98] | 0.005 |
DAP–mmHg | 54 [48–65] | 61 [52–73] | 0.01 |
CVP–mmHg | 8 [6–10] | 10 [8–15] | 0.002 |
CI–L/min/m2 | 2.71 [2.24–2.99] | 2.73 [2.31–3.03] | 0.73 |
HR–beats/min | 104 [91–122] | 100 [84–114] | 0.006 |
Blood temperature–°C | 36.8 [35.5–37.2] | 36.7 [35.3–37.0] | 0.001 |
Lactate–mmol/L | 4.6 [2.4–5.7] | – | – |
Norepinephrine | |||
Rate–µg/kg/min | 0.79 [0.47–1.79] | 0.79 [0.47–1.79] | – |
Delay between initiation and CRT–hour | 22 [11–39] | – | – |
CRT–s | 4.82 [3.16–7.45] | 4.43 [3.01–7.44] | 0.09 |