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Table 3 Factors associated with ICU mortality for iGAS infections

From: Invasive group A streptococcal infections requiring admission to ICU: a nationwide, multicenter, retrospective study (ISTRE study)

Variables

Multivariate analysis

OR

CI95%

p value

Diabetes

3.92

1.42–10.79

0.008

Immunosuppression

4.02

1.03–15.59

0.044

STSS

5.75

1.71–19.22

0.005

Invasive mechanical ventilation

6.08

1.71–21.60

0.005

Acute kidney injury

4.85

1.05–22.42

0.043

  1. Statistical significance (p < 0.05)
  2. CI confidence interval, ICU intensive care unit, OR odds ratio, STSS streptococcal toxic shock syndrome
  3. Univariate comparison was performed using linear logistic regression (Table S1). Independent variables with a p value < 0.20 were considered for inclusion in the multivariate analysis using linear logistic regression. We excluded “renal replacement therapy” variable due to collinearity with “acute kidney injury” variable. We applied a backward stepwise selection for period, age, diabetes, immunosuppression, infection site, STSS, invasive mechanical ventilation, dobutamine use and acute kidney injury to identify factors significantly associated with ICU mortality in iGAS patients. The ratio was of one independent variable for 8 events
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Critical Care

ISSN: 1364-8535