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Table 1 Baseline characteristics of AIS patients complicating AMI

From: Remote ischemic conditioning reduces adverse events in patients with acute ischemic stroke complicating acute myocardial infarction: a randomized controlled trial

Characteristic

RIC

(N = 37)

Sham-RIC

(N = 40)

p value

Age—yr

74.97 ± 11.55

74.75 ± 11.58

0.933

Male sex—no. (%)

23 (62.2%)

24 (60.0%)

0.846

Admission SBP, mmHg

130.49 ± 27.93

130.40 ± 25.68

0.989

Admission DBP, mmHg

74.16 ± 15.54

71.80 ± 16.13

0.515

Serum glucose, mmol/L

7.48 ± 2.78

8.50 ± 4.44

0.233

LDL, mmol/L

2.36 ± 0.86

2.43 ± 1.13

0.738

hs-CRP, mg/L

16.20 (8.21–30.50)

30.50 (5.95–40.54)

0.230

Vascular risk factor

Hypertension, n (%)

30 (81.1%)

25 (62.5%)

0.071

Diabetes, n (%)

13 (35.1%)

15 (37.5%)

0.829

Hyperlipidemia, n (%)

9 (24.3%)

12 (30.0%)

0.576

Arrhythmia, n (%)

13 (35.1%)

16 (40%)

0.660

Atrial fibrillation, n (%)

7 (18.9%)

10 (25%)

0.520

Smoke, n (%)

10 (27.0%)

15 (37.5%)

0.327

Alcohol, n (%)

4 (10.8%)

6 (15%)

0.585

History of prior coronary heart disease, n (%)

20 (54.1%)

17 (42.5%)

0.311

Prior ischemic stroke, n (%)

15 (40.5%)

19 (47.5%)

0.539

Pre-stroke antithrombotic therapy

None, n (%)

9 (24.3%)

11 (27.5%)

0.751

Single antiplatelet, n (%)

25 (67.6%)

29 (72.5%)

0.637

Dual antiplatelet, n (%)

3 (8.1%)

0 (0.0%)

0.106

Location of AIS

0.818

Anterior circulation, n (%)

25 (67.6%)

28 (70.0%)

 

Posterior circulation, n (%)

12 (32.4%)

12 (30.0%)

 

Stroke etiology*

0.884

Large-artery atherosclerosis, n (%)

24 (64.9%)

26 (65.0%)

 

Cardioembolism, n (%)

5 (13.5%)

6 (15.0%)

 

Small-vessel occlusion, n (%)

5 (13.5%)

4 (10.0%)

 

Stroke of other determined etiology, n (%)

0 (0%)

1 (2.5%)

 

Stroke of undetermined etiology, n (%)

3 (8.1%)

3 (7.5%)

 

Intracranial artery stenosis, n (%)^

18 (48.7%)

18 (45%)

0.749

Acute coronary syndrome type

0.642

STEMI, n (%)

6 (16.2%)

5 (12.5%)

 

NSTEMI, n (%)

31 (83.8%)

35 (87.5%)

 

Severity of AMI

GRACE score

177.0 (160.0–194.5)

190.5 (163.3–206.5)

0.155

Severity of stroke

NHISS score

8 (4–12)

6.25 (4.25–14)

0.810

mRS score

4 (3.5–5)

4 (4–4)

0.787

LVEF, %

63.0 (49.0–67.0)

57.1 (51.0–66.0)

0.588

Stroke onset to enrollment, h

17.00 (13.00–20.00)

19.75 (12.00–22.38)

0.232

Stroke onset to RIC treatment, h

18.00 (14.00–21.50)

21.00 (13.50–23.60)

0.245

  1. RIC remote ischemic conditioning, SBP systolic blood pressure, DBP diastolic blood pressure, LDL low-density lipoprotein, hs-CRP high-sensitivity C-reactive protein, AIS acute ischemic stroke, AMI acute myocardial infarction, STEMI segment elevation myocardial infarction, NSTEMI non-segment elevation myocardial infarction, NIHSS National Institutes of Health Stroke Scale, mRS modified Rankin Scale, LVEF Left ventricular ejection fraction
  2. *Clarified based on TOAST criteria
  3. ^Refer to intracranial artery stenosis that cause the indexed ischemic stroke event