Skip to main content
Fig. 2 | Critical Care

Fig. 2

From: Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial

Fig. 2

Clinical outcomes by latent class analysis (LCA) subtype assignment. A Mortality rates by subtype assignment stratified by WHO ordinal scale for COVID-19 severity upon trial enrollment; Within strata comparisons done using Chi-squared test or Fisher’s exact test where appropriate and p-value < 0.05 is depicted via Asterix. B Survival and recovery for Subtype 2 compared with Subtype 1 stratified by WHO ordinal scale for COVID-19 severity upon trial enrollment; For time to death, estimates are derived from Fine-Gray subdistribution hazard model with recovery as the competing event; For time to recovery, estimates are derived from Fine-Gray subdistribution hazard model with death as the competing event. ***P value < 0.001. WHO 5: hospitalized, noninvasive mechanical ventilation or high-flow nasal cannula (HFNC); WHO 6: hospitalized, intubation and invasive mechanical ventilation (IMV); WHO 7: hospitalized, IMV + additional support such as pressors or extracardiac membranous oxygenation

Back to article page

Critical Care

ISSN: 1364-8535