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Fig. 3 | Critical Care

Fig. 3

From: Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial

Fig. 3

Change in log10 biomarker concentration over time by subtype assignment in the control arm (N = 142). A Biomarkers of inflammation, B endothelial injury, C alveolar epithelial injury, and D disordered coagulation. Y-axis is the log10 concentration of biomarker. Estimates with 95% confidence intervals derived from linear mixed effects models. Asterisks denote significant difference in the slope of biomarker change over time between Subtype 1 and Subtype 2 based on Chi-squared test of interaction. *p value < 0.05. **p value < 0.005. ***p value < 0.001

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Critical Care

ISSN: 1364-8535