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Table 3 Weaning from tMCS in HF-CS

From: The management of heart failure cardiogenic shock: an international RAND appropriateness panel

Statements

Median

Disagreement index (DI)

Inter-percentile range (IPR)

RAND panel outcome

Regarding the weaning of tMCS in HF-CS, please rate the appropriateness of the following:

Routine PAC to assess / support weaning of tMCS

7.0

0.08

1.00

Appropriate

At least one attempt to wean tMCS before decision to transition to AHF therapies

7.5

0.23

2.00

Appropriate

Routine echocardiogram to assess / support weaning of tMCS

7.0

0.16

1.25

Appropriate

Use of Levosimendan to support weaning of tMCS

4.5

0.59

3.25

Uncertain

Use of escalating inotropes to wean from tMCS

6.0

0.35

2.00

Uncertain

Use of intravenous vasodilators to support weaning from tMCS

6.5

0.35

2.00

Appropriate

Trial of endothelin receptor antagonists or phosphodiesterase inhibitors in patients with evidence of pulmonary hypertension to support weaning from tMCS

5.0

0.43

2.25

Uncertain

  1. For each question, median scores were allocated as inappropriate if scoring <3.5, uncertain if ≥3.5 and <6.5 uncertain and appropriate if ≥6.5. DI was calculated using the RAND DI and disagreement deemed if DI ≥1 amongst the panellists.
  2. HF-CS, Heart Failure related Cardiogenic Shock; PAC, Pulmonary Artery Catheterisation; tMCS, temporary Mechanical Circulatory Support; VAD, Ventricular Assist Device