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Table 1 Patient characteristics

From: Plasma glial fibrillary acidic protein and tau: predictors of neurological outcome after cardiac arrest

 

OHCA (n = 328)

IHCA (n = 100)

p-value

Age, year—median

67 [59–75]

71 [59–77]

0.09

Sex, Male

247 (75.3)

63 (63.0)

0.02

Medical history

   

Myocardial infarction

50 (15.2)

19 (19.0)

0.46

Congestive heart failure

52 (15.9)

26 (26.0)

0.03

Hypertension

124 (37.8)

48 (48.0)

0.09

Liver disease

6 (1.8)

4 (4.0)

0.40

Renal disease

24 (7.3)

18 (18.0)

0.003

Diabetes

66 (20.1)

37 (37.0)

0.001

Cerebrovascular disease

25 (7.6)

15 (15.0)

0.04

Dementia/cognitive impairment

13 (4.0)

6 (6.0)

0.56

Solid tumour

31 (9.5)

17 (17.0)

0.06

Cardiac arrest variables

   

Minutes to ROSC—median

25 [15–40]

10 [6–20]

 < 0.001

Witnessed cardiac arrest

256 (78.0)

83 (83.0)

0.35

Bystander CPR

206 (62.8)

N/A

N/A

Arrest with medical personnel present

39 (11.9)

100 (100.0)

N/A

Shockable rhythm

177 (54.1)c

21 (21.2)c

 < 0.001

Cardiac causea

246 (75.0)

38 (38.0)

 < 0.001

Admission data

   

GCS-M—median

1 [1, 2]g

3 [1–5]e

 < 0.001

Circulatory shock

103 (31.4)

32 (32.0)

1.00

ICU data

   

Patients regaining consciousness

128 (39.3)d

66 (66)

 < 0.001

Days from CA to awakening

1 [1, 2]e

1 [0–2]

0.001

WLSTb

181 (55.2)

34 (34.0)c

 < 0.001

WLST due to poor neurological prognosis

159 (48)f

26 (26)d

 < 0.001

Days from CA to WLST

4 [2–5]f

4 [3–6]d

0.15

Follow-up

   

Good outcome, CPC 1–2

105 (32.0)

45 (45.0)

0.02

Poor outcome, CPC 3–5

223 (68.0)

55 (55.0)

0.02

  1. Continuous variables are presented as median [interquartile range] and categorical variables as n (%). Proportions (%) are within the groups of OHCA and IHCA patients
  2. aRetrospectively diagnosed during the hospital stay
  3. bThere can be multiple reasons for WLST, including neurological, circulatory, multi-organ failure, comorbidities, or ethical reasons
  4. Missing data: cn = 1, dn = 2, en = 3, fn = 4, gn = 5
  5. ROSC return of spontaneous circulation, GCS-M Glasgow Coma Scale Motor response, ICU intensive care unit, CPC Cerebral Performance Category, WLST withdrawal of life-sustaining therapy, CA cardiac arrest OHCA out-of-hospital cardiac arrest, IHCA in-hospital cardiac arrest