Table 3 Multiple logistic regression for predicting favorable neurological outcomes with (a) the manual method and (b) the automated method
| Â | Derivation | Validation | Total | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Odds ratio | \(95\%\) C.I. | P value | Odds ratio | \(95\%\) C.I. | P value | Odds ratio | \(95\%\) C.I. | P value |
(a) With the manual method | |||||||||
Manual_s \(>1.252\) | 4.13 | 1.90–8.97 | \(<0.001\) | 3.11 | 1.33–7.22 | 0.009 | 3.27 | 1.94–5.53 | \(<0.001\) |
Age | 0.98 | 0.95–1.00 | 0.107 | 0.97 | 0.95–1.00 | 0.041 | 0.97 | 0.96–0.99 | 0.006 |
Male | 1.43 | 0.62–3.28 | 0.398 | 1.52 | 0.54–4.31 | 0.429 | 1.23 | 0.68–2.25 | 0.496 |
HTN | 0.80 | 0.32–1.97 | 0.621 | 1.57 | 0.52–4.76 | 0.426 | 1.03 | 0.53–1.98 | 0.940 |
Malignancy | 0.15 | 0.02–0.86 | 0.033 | 1.20 | 0.29–4.98 | 0.802 | 0.38 | 0.14–1.07 | 0.068 |
Witnessed collapse | 1.24 | 0.48–3.17 | 0.659 | 2.12 | 0.63–7.11 | 0.225 | 1.35 | 0.68–2.68 | 0.396 |
Epinephrine dose (mg) | 0.60 | 0.48–0.75 | \(<0.001\) | 0.86 | 0.74–1.01 | 0.064 | 0.73 | 0.64–0.82 | \(<0.001\) |
CPR duration | 1.00 | 0.97–1.04 | 0.984 | 0.95 | 0.91–0.99 | 0.023 | 0.98 | 0.96–1.01 | 0.197 |
DBP | 1.04 | 1.01–1.06 | 0.005 | 1.02 | 0.99–1.06 | 0.209 | 1.02 | 1.01–1.04 | 0.007 |
SBP | 0.99 | 0.97–1.00 | 0.139 | 1.01 | 0.99–1.03 | 0.556 | 1.00 | 0.98–1.01 | 0.410 |
pH value | 14.05 | 0.77–256.51 | 0.074 | 11.51 | 0.47–283.27 | 0.135 | 6.60 | 0.88–49.64 | 0.067 |
Lactic acid | 1.00 | 0.90–1.13 | 0.941 | 0.90 | 0.81–1.01 | 0.064 | 0.95 | 0.88–1.02 | 0.125 |
Troponin (ng/L) | 0.96 | 0.93–0.99 | 0.009 | 1.00 | 0.99–1.00 | 0.502 | 0.99 | 0.98–1.00 | 0.069 |
ECMO | 7.53 | 2.21–25.69 | 0.001 | 4.45 | 1.48–13.34 | 0.008 | 5.23 | 2.39–11.41 | \(<0.001\) |
(b) With the automated method | |||||||||
Automated_s \(>1.204\) | 5.69 | 2.57–12.59 | \(<0.001\) | 4.81 | 1.94–11.90 | 0.001 | 5.22 | 2.96–9.19 | \(<0.001\) |
Age | 0.99 | 0.96–1.01 | 0.298 | 0.97 | 0.95–1.00 | 0.062 | 0.98 | 0.96–1.00 | 0.035 |
Male | 1.38 | 0.59–3.21 | 0.453 | 1.61 | 0.54–4.79 | 0.396 | 1.28 | 0.69–2.38 | 0.436 |
HTN | 0.74 | 0.29–1.88 | 0.521 | 1.32 | 0.44–3.94 | 0.616 | 1.00 | 0.51–1.96 | 0.995 |
Malignancy | 0.10 | 0.02–0.64 | 0.015 | 1.81 | 0.43–7.60 | 0.419 | 0.40 | 0.14–1.13 | 0.085 |
Witnessed collapse | 1.67 | 0.64–4.36 | 0.294 | 2.40 | 0.67–8.63 | 0.179 | 1.58 | 0.78–3.23 | 0.206 |
Epinephrine dose (mg) | 0.63 | 0.51–0.78 | \(<0.001\) | 0.88 | 0.75–1.04 | 0.142 | 0.75 | 0.66–0.85 | \(<0.001\) |
CPR duration | 0.99 | 0.95–1.03 | 0.500 | 0.95 | 0.91–0.99 | 0.024 | 0.97 | 0.95–1.00 | 0.073 |
DBP | 1.04 | 1.01–1.06 | 0.007 | 1.02 | 0.98–1.05 | 0.374 | 1.02 | 1.00–1.04 | 0.020 |
SBP | 0.98 | 0.97–1.00 | 0.064 | 1.01 | 0.99–1.03 | 0.497 | 0.99 | 0.98–1.01 | 0.353 |
pH value | 4.82 | 0.24–98.17 | 0.307 | 5.42 | 0.21–141.74 | 0.310 | 2.96 | 0.36–24.15 | 0.310 |
Lactic acid | 0.96 | 0.85–1.08 | 0.470 | 0.91 | 0.82–1.01 | 0.081 | 0.93 | 0.87–1.00 | 0.062 |
Troponin (ng/L) | 0.97 | 0.94–1.00 | 0.038 | 1.00 | 0.99–1.01 | 0.583 | 0.99 | 0.98–1.00 | 0.075 |
ECMO | 5.12 | 1.50–17.47 | 0.009 | 3.46 | 1.09–10.96 | 0.035 | 3.98 | 1.78–8.90 | \(<0.001\) |