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Fig. 2 | Critical Care

Fig. 2

From: Impact of attaining aggressive vs. conservative PK/PD target on the clinical efficacy of beta-lactams for the treatment of Gram-negative infections in the critically ill patients: a systematic review and meta-analysis

Fig. 2

Significant independent predictors of failure in attaining aggressive PK/PD targets of beta-lactams. A risk score ranging from − 2 to 6 points was developed and proposed. ARC: augmented renal clearance; BMI: body mass index; CB: clinical breakpoint; MIC: minimum inhibitory concentration; OR: odds ratio; PK/PD: pharmacokinetic/pharmacodynamic

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Critical Care

ISSN: 1364-8535