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  1. Retrospective studies have demonstrated that the deep learning-based cardiac arrest risk management system (DeepCARS™) is superior to the conventional methods in predicting in-hospital cardiac arrest (IHCA). T...

    Authors: Kyung-Jae Cho, Jung Soo Kim, Dong Hyun Lee, Sang‑Min Lee, Myung Jin Song, Sung Yoon Lim, Young-Jae Cho, You Hwan Jo, Yunseob Shin and Yeon Joo Lee
    Citation: Critical Care 2023 27:346
    Content type: Research Published on:

  2. Respiratory mechanics is a key element to monitor mechanically ventilated patients and guide ventilator settings. Besides the usual basic assessments, some more complex explorations may allow to better charact...

    Authors: François M. Beloncle, Jean-Christophe Richard, Hamid Merdji, Christophe Desprez, Bertrand Pavlovsky, Elise Yvin, Lise Piquilloud, Pierre-Yves Olivier, Dara Chean, Antoine Studer, Antonin Courtais, Maëva Campfort, Hassene Rahmani, Arnaud Lesimple, Ferhat Meziani and Alain Mercat
    Citation: Critical Care 2023 27:343
    Content type: Research Published on:

  4. Approximately 20% of patients with acute brain injury (ABI) also experience acute kidney injury (AKI), which worsens their outcomes. The metabolic and inflammatory changes associated with AKI likely contribute...

    Authors: Faeq Husain-Syed, Tomonori Takeuchi, Javier A. Neyra, Gonzalo Ramírez-Guerrero, Mitchell H. Rosner, Claudio Ronco and Ashita J. Tolwani
    Citation: Critical Care 2023 27:341
    Content type: Review Published on:

  5. Except in a few retrospective studies mainly including patients under chemotherapy, information regarding the impact of immunosuppressive therapy on the prognosis of patients admitted to the intensive care uni...

    Authors: Julien Vaidie, Edwige Peju, Louise-Marie Jandeaux, Mathieu Lesouhaitier, Jean-Claude Lacherade, Antoine Guillon, Xavier Wittebole, Pierre Asfar, Bruno Evrard, Thomas Daix, Philippe Vignon and Bruno François
    Citation: Critical Care 2023 27:340
    Content type: Research Published on:

  6. The primary aim was to explore the association of global cerebral physiological variables including intracranial pressure (ICP), cerebrovascular reactivity (PRx), cerebral perfusion pressure (CPP), and deviati...

    Authors: Teodor Svedung Wettervik, Erta Beqiri, Stefan Yu Bögli, Michal Placek, Mathew R. Guilfoyle, Adel Helmy, Andrea Lavinio, Ronan O’Leary, Peter J. Hutchinson and Peter Smielewski
    Citation: Critical Care 2023 27:339
    Content type: Research Published on:

    The Matters Arising to this article has been published in Critical Care 2023 27:452

  7. Few specific methods are available to reduce the risk of diaphragmatic dysfunction for patients under mechanical ventilation. The number of studies involving transcutaneous electrical stimulation of the diaphr...

    Authors: Clément Medrinal, Margaux Machefert, Bouchra Lamia, Tristan Bonnevie, Francis-Edouard Gravier, Roger Hilfiker, Guillaume Prieur and Yann Combret
    Citation: Critical Care 2023 27:338
    Content type: Research Published on:

  14. Vascular leakage is a major feature of acute respiratory distress syndrome (ARDS). We aimed to evaluate the efficacy of FX06, a drug under development that stabilizes interendothelial cell junctions, at reduci...

    Authors: Emmanuelle Guérin, Lisa Belin, Guillaume Franchineau, Loïc Le Guennec, David Hajage, Mamadou Hassimiou Diallo, Thomas Frapard, Lucie Le Fèvre, Charles-Edouard Luyt, Alain Combes, Stéphane Germain, Jan Hayon, Pierre Asfar and Nicolas Bréchot
    Citation: Critical Care 2023 27:331
    Content type: Research Published on:

  16. Haloperidol is frequently used in critically ill patients with delirium, but evidence for its effects has been sparse and inconclusive. By including recent trials, we updated a systematic review assessing effe...

    Authors: Nina Christine Andersen-Ranberg, Marija Barbateskovic, Anders Perner, Marie Oxenbøll Collet, Lone Musaeus Poulsen, Mathieu van der Jagt, Lisa Smit, Jørn Wetterslev, Ole Mathiesen and Mathias Maagaard
    Citation: Critical Care 2023 27:329
    Content type: Research Published on:

  17. Cognitive impairment is common following out-of-hospital cardiac arrest (OHCA), but the nature of the impairment is poorly understood. Our objective was to describe cognitive impairment in OHCA survivors, with...

    Authors: Erik Blennow Nordström, Susanna Vestberg, Lars Evald, Marco Mion, Magnus Segerström, Susann Ullén, John Bro-Jeppesen, Hans Friberg, Katarina Heimburg, Anders M. Grejs, Thomas R. Keeble, Hans Kirkegaard, Hanna Ljung, Sofia Rose, Matthew P. Wise, Christian Rylander…
    Citation: Critical Care 2023 27:328
    Content type: Research Published on:

  20. Mechanical ventilation is applied to unload the respiratory muscles, but knowledge about transpulmonary driving pressure (ΔPL) is important to minimize lung injury. We propose a method to estimate ΔPL during neur...

    Authors: Ling Liu, Hong-Liang Li, Cong Lu, Purab Patel, Danqiong Wang, Jennifer Beck and Christer Sinderby
    Citation: Critical Care 2023 27:325
    Content type: Research Published on:

  22. Pneumocystis jirovecii pneumonia (PJP) is an opportunistic, life-threatening disease commonly affecting immunocompromised patients. The distribution of predisposing diseases or conditions in critically ill patien...

    Authors: Daniele Roberto Giacobbe, Silvia Dettori, Vincenzo Di Pilato, Erika Asperges, Lorenzo Ball, Enora Berti, Ola Blennow, Bianca Bruzzone, Laure Calvet, Federico Capra Marzani, Antonio Casabella, Sofia Choudaly, Anais Dartevel, Gennaro De Pascale, Gabriele Di Meco, Melissa Fallon…
    Citation: Critical Care 2023 27:323
    Content type: Research Published on:

  24. Thrombocytopenia, hemorrhage and platelet transfusion are common in patients supported with venoarterial extracorporeal membrane oxygenation (VA ECMO). However, current literature is limited to small single-ce...

    Authors: Senta Jorinde Raasveld, Claudia van den Oord, Jimmy Schenk, Walter M. van den Bergh, Annemieke Oude Lansink - Hartgring, Franciska van der Velde, Jacinta J. Maas, Pablo van de Berg, Roberto Lorusso, Thijs S. R. Delnoij, Dinis Dos Reis Miranda, Erik Scholten, Fabio Silvio Taccone, Dieter F. Dauwe, Erwin De Troy, Greet Hermans…
    Citation: Critical Care 2023 27:321
    Content type: Research Published on:

  25. COVID-19 patients with acute hypoxemic respiratory failure (AHRF) benefit from high flow nasal cannula (HFNC) oxygen therapy. However, delays in initiating invasive ventilation after HFNC failure are associate...

    Authors: Chun En Yau, Dawn Yi Xin Lee, Adithi Vasudevan, Ken Junyang Goh, Evelyn Wong, Andrew Fu Wah Ho and Daniel Yan Zheng Lim
    Citation: Critical Care 2023 27:320
    Content type: Research Published on:

  27. Urinary C–C motif chemokine ligand 14 (CCL14) has been described as an effective marker for delayed recovery of acute kidney injury (AKI), yet its efficacy has been found to vary between different trials. The ...

    Authors: Yih‑Ting Chen, Heng-Chih Pan, Cheng-Kai Hsu, Chiao-Yin Sun, Chun-Yu Chen, Yi-Hung Chen, Heng-Jung Hsu, I-Wen Wu, Vin-Cent Wu and Eric Hoste
    Citation: Critical Care 2023 27:318
    Content type: Research Published on:

  29. This substudy of the randomized IDEAL-ICU trial assessed whether the timing of renal replacement therapy (RRT) initiation has a differential effect on 90-day mortality, according to the criteria used to diagno...

    Authors: Saber Davide Barbar, Abderrahmane Bourredjem, Rémi Trusson, Auguste Dargent, Christine Binquet and Jean-Pierre Quenot
    Citation: Critical Care 2023 27:316
    Content type: Research Published on:

  30. The effects of awake prone position on the breathing pattern of hypoxemic patients need to be better understood. We conducted a crossover trial to assess the physiological effects of awake prone position in pa...

    Authors: Domenico Luca Grieco, Luca Delle Cese, Luca S. Menga, Tommaso Rosà, Teresa Michi, Gianmarco Lombardi, Melania Cesarano, Valentina Giammatteo, Giuseppe Bello, Simone Carelli, Salvatore L. Cutuli, Claudio Sandroni, Gennaro De Pascale, Antonio Pesenti, Salvatore M. Maggiore and Massimo Antonelli
    Citation: Critical Care 2023 27:315
    Content type: Research Published on:

  32. Serum neuron-specific enolase (NSE) is the only recommended biomarker for multimodal prognostication in postcardiac arrest patients, but low sensitivity of absolute NSE threshold limits its utility. This study...

    Authors: Youn-Jung Kim, Yong Hwan Kim, Chun Song Youn, In Soo Cho, Su Jin Kim, Jung Hee Wee, Yoo Seok Park, Joo Suk Oh, Byung Kook Lee and Won Young Kim
    Citation: Critical Care 2023 27:313
    Content type: Research Published on:

  33. Anticoagulants are widely used but can lead to iatrogenic events such as bleeding. Limited data exists regarding the characteristics and management of patients admitted to intensive care units (ICU) for severe...

    Authors: Thomas Botrel, Sibylle Cunat, Julie Helms, Jérémie Lemarié, Jeanne Gaillon, Sébastien Préau, Raphael Favory, Arnaud W. Thille, Florence Boissier, Eric Maury, Jérémie Joffre and Hafid Ait-Oufella
    Citation: Critical Care 2023 27:312
    Content type: Research Published on:

    The Matters Arising to this article has been published in Critical Care 2023 27:356

  35. Authors: Leandro Moreira Peres, Fabio Luis-Silva, Mayra Gonçalves Menegueti, Wilson José Lovato, Douglas Alexandre do Espirito Santo, Mariana Derminio Donadel, Lucas Sato, Carolina Hunger Malek-Zadeh, Anibal Basile-Filho, Olindo Assis Martins-Filho and Maria Auxiliadora-Martins
    Citation: Critical Care 2023 27:310
    Content type: Correspondence Published on:

  37. Conflicting findings exist regarding the influence of sex on the development, treatment, course, and outcome of status epilepticus (SE). Our study aimed to investigate sex-related disparities in adult SE patie...

    Authors: Sira M. Baumann, Pia De Stefano, Paulina S. C. Kliem, Pascale Grzonka, Caroline E. Gebhard, Oana E. Sarbu, Gian Marco De Marchis, Sabina Hunziker, Stephan Rüegg, Andreas Kleinschmidt, Jérôme Pugin, Hervé Quintard, Stephan Marsch, Margitta Seeck and Raoul Sutter
    Citation: Critical Care 2023 27:308
    Content type: Research Published on:

  38. Positive end-expiratory pressure (PEEP) individualized to a maximal respiratory system compliance directly implies minimal driving pressures with potential outcome benefits, yet, raises concerns on static and ...

    Authors: Congli Zeng, Min Zhu, Gabriel Motta-Ribeiro, David Lagier, Takuga Hinoshita, Mingyang Zang, Kira Grogg, Tilo Winkler and Marcos F. Vidal Melo
    Citation: Critical Care 2023 27:307
    Content type: Research Published on:

  42. Ventilator-free days (VFDs) are a composite endpoint increasingly used as the primary outcome in critical care trials. However, because of the skewed distribution and competitive risk between components, sampl...

    Authors: Laurent Renard Triché, Emmanuel Futier, Manuela De Carvalho, Nathalie Piñol-Domenech, Laëtitia Bodet-Contentin, Matthieu Jabaudon and Bruno Pereira
    Citation: Critical Care 2023 27:303
    Content type: Research Published on:

  43. Sepsis survivors are at elevated risk for cardiovascular disease during long-term follow-up. Whether diabetes influences cardiovascular risk after sepsis survival remains unknown. We sought to describe the ass...

    Authors: Federico Angriman, Patrick R. Lawler, Baiju R. Shah, Claudio M. Martin and Damon C. Scales
    Citation: Critical Care 2023 27:302
    Content type: Research Published on:

  44. Intensive Care Unit (ICU) survivors often experience several impairments in their physical, cognitive, and psychological health status, which are labeled as post-intensive care syndrome (PICS). The aim of this...

    Authors: Caroline Renner, Marie-Madlen Jeitziner, Monika Albert, Sabine Brinkmann, Karin Diserens, Imanuel Dzialowski, Maria-Dorothea Heidler, Martina Lück, Ricki Nusser-Müller-Busch, Peter S. Sandor, Andreas Schäfer, Bettina Scheffler, Claus Wallesch, Gudrun Zimmermann and Peter Nydahl
    Citation: Critical Care 2023 27:301
    Content type: Guideline Published on:

  45. Albumin infusion is the primary therapeutic strategy for septic patients with liver cirrhosis. Although recent studies have investigated the efficacy of albumin in the resuscitation stage of septic patients wi...

    Authors: Wenhan Hu, Hui Chen, Chencheng Ma, Qin Sun, Meicheng Yang, Haofei Wang, Qingyun Peng, Jinlong Wang, Chen Zhang, Wei Huang, Jianfeng Xie and Yingzi Huang
    Citation: Critical Care 2023 27:300
    Content type: Research Published on:

  46. The Netherlands introduced an opt-out donor system in 2020. While the default in (presumed) consent cases is donation, family involvement adds a crucial layer of influence when applying this default in clinica...

    Authors: Sanne P. C. van Oosterhout, Anneke G. van der Niet, W. Farid Abdo, Marianne Boenink, Thomas G. V. Cherpanath, Jelle L. Epker, Angela M. Kotsopoulos, Walther N. K. A. van Mook, Hans P. C. Sonneveld, Meint Volbeda, Gert Olthuis and Jelle L. P. van Gurp
    Citation: Critical Care 2023 27:299
    Content type: Research Published on:

  50. Prognostication is very important to clinicians and families during the early management of severe traumatic brain injury (sTBI), however, there are no gold standard biomarkers to determine prognosis in sTBI. ...

    Authors: Mohammad M. Banoei, Chel Hee Lee, James Hutchison, William Panenka, Cheryl Wellington, David S. Wishart and Brent W. Winston
    Citation: Critical Care 2023 27:295
    Content type: Research Published on:
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  • ISSN: 1364-8535 (electronic)

Critical Care

ISSN: 1364-8535